Is aloin toxic? It hurts? In which cases it is contraindicated

Pubblicato : 11/06/2017 15:33:35
Categorie : Aloe , Erbe della salute

aloin toxic

"Is it true that aloin hurts and is toxic to the body ?

In this regard I would like to respond to you by quoting a famous aphorism by Joseph Goebbels:

Repeat a lie a hundred, a thousand, a million times and it will become a truth .

Even without validating scientific evidence, if we are told over and over again that something is true, it is easy for us to end up believing it.

And that's exactly what happened with the aloin !

What the aloin is toxic, is nothing but a story for purely commercial purposes, set up and repeated endlessly by a well-known American company that produces and markets products based on Aloe Vera.

In reality it is not absolutely true that aloin is toxic, there is no scientific evidence to prove it.

Instead, there are several studies showing that aloin is a potent antitumor and natural antimicrobial.

What is true, however, is that some people may be particularly sensitive to this substance, whose intake, at least at the beginning, can lead to some side effects such as diarrhea.

So, at least initially, if you have these problems, you should start with an intake at reduced doses of Aloe juice, but do not eliminate aloin altogether.

Finally there are cases, which we will then see, in which the aloin is completely contraindicated .

What is aloin?

aloina hurts

Aloin is a yellowish and viscous substance with a pungent odor and bitter taste, present in the peel and in the outer layer of gel of Aloe leaves.

We find it both in Aloe Vera, in Aloe Arborescens, but also in many other varieties of Aloe.

It is a molecule that is part of the group of anthraquinones , substances that act as a "defense mechanism for plants" against the attack of insects and various parasites.

And in fact these substances have important antimicrobial properties, useful for the defenses of the plant itself, but that can also be exploited by us humans.

The main molecules that are part of the group of anthraquinones, contained in the Aloe, are:

  • Aloetic acid : presents a natural antibiotic action, especially in association with the other anthraquinones present in the aloe;
  • Cinnamic acid : with intense antibacterial activity, effective against various pathogenic bacteria such as those of the salmonella genus, streptococci and staphylococci;
  • Chrysophanic acid : it is a good purifying, diuretic, laxative, with eupeptic and toning properties;
  • Aloemodine : has important cytotoxic effects especially against precancerous and cancerous cells of particular tumors, as numerous experimental observations in vitro and in vivo have shown;
  • Aloin : comes in the form of two isomers referred to as Aloin A and B. It has action, as well as laxative, also detoxifying, antibiotic and antitumor.

All these substances, incredibly useful for our body, are eliminated by many producers of Aloe juices, with the excuse that they are toxic substances.

But the truth is another ...

Why do they keep saying that aloin is toxic?

There are two main reasons:

1 - Unpleasant taste and odor

Aloe vera without aloin The truth is that the aloin and in general all the anthraquinones present in the Aloe have 2 major defects:

  • a very bitter taste ;
  • a very pungent smell .

Commercially these characteristics are unpleasant by consumers and this is a problem for those companies whose sole objective is to sell and generate profit.

And this is the real reason that pushed these companies to use only Aloe gel and not the whole leaf.

And very often these companies, in order to improve the taste of their products, add other ingredients such as sugar, sweeteners, flavorings and fruit juices of low quality, ending up with the alteration of the organoleptic properties of the final product, to the detriment of the benefits .

2 - Laxative properties

It is true, the aloin has laxative properties .

In fact, the pharmaceutical industry uses it for the preparation of powders and tablets with a laxative effect.

These drugs , if used excessively and continuously , can irritate the walls of the intestine and the long-term effects can also be dangerous .

However, we are talking about an extracted and isolated molecule, not of the Aloe leaf taken in its entirety , where the aloin represents only a very small part.

However, because of the laxative properties of the aloe, the companies and retailers of products based on Aloe Vera gel have thought well to catch the ball, starting to tell the story that the aloin would be even toxic to the body.

All with the sole objective of dissuading you from using your Aloe plants, in favor of their products , based on the "pure gel" deprived of alkali, often using conventional techniques, such as the use of activated carbon filters. and pasteurization, procedures that improve storage times, but which destroy most of the active ingredients of Aloe, drastically reducing the benefits.

 The truth is that aloin can be harmful if:

  • it exaggerates with dosages : aloin overdose can create diarrhea phenomena, but it is well known that abuse and the disproportionate use of anything is harmful and harmful to our person. Even water can be harmful if taken in excess;
  • they are taking alaloin drugs : in this case we are not talking about the intake of the Aloe leaf, or of its juice, but of the aloin molecule, extracted in the laboratory for the production of powders and tablets, sold in pharmacies and herbalists;
  • one is suffering from colitis, ulcerative colitis, or crohn's disease : in these cases it is better to avoid totally the aloin, as it can be particularly irritating to the intestinal walls, already inflamed because of the disease.

With the words "pure Aloe gel, without aloin", these companies delude you, making you believe that they are offering you a product with a high "added value".

The truth is that these products, in 100% of cases, are far lower than the juice that you could easily make at home , with your Aloe plants, grown in pots or in the garden.

Take a preparation made with the whole leaf allows you to benefit from the whole set of active ingredients present in the Aloe and not only from the gel.

And it is no coincidence that Father Romano Zago (the greatest supporter of the beneficial properties of the Aloe), in his two books " Di Cancro can be cured " and " Aloe is not a medicine ... but it heals ", strongly advises the preparation juice, using the entire Aloe leaf, preferably using the Aloe Arborescens variety.

In fact, Aloe Arborescens contains up to three times the active ingredients present in Aloe Vera.

In this short piece of video, Father Zago answers precisely the question " Can aloe be toxic? Is aloin toxic? ".

Why take Aloe in its entirety?

The concepts I will explain to you now apply to Aloe, as they apply to any other medicinal plant.

To answer the question I will rely on the text " Phytosanitary: Rational Use of Plant Drugs " written by Prof. Francesco Capasso, Prof. Giuliano Grandolini, Prof. Angelo A. Izzo, three of the leading experts in phytotherapy in Italy.

1 - The presence of substances of minimal interest, but very important

Excerpt from the chapter: The complexity of the natural drug

The goodness of a plant drug * is directly related to its content in active ingredients .

* NB : the word "drug plant" is used to indicate a plant or part of it, stored in the dry state, and used for therapeutic use.

In the drug, however, there are many other substances that give it a particular therapeutic physiognomy difficult to reproduce in the laboratory .

These are inactive substances, or of minimal pharmacological interest such as bitter or aromatic substances which, exalting the secretions of the gastrointestinal tract, facilitate the dissolution and absorption of the active ingredients.

Reporting it to our case means that in the Aloe there are many substances that are inactive, or of minimal pharmacological interest are fundamental.

In particular, the aloin (bitter substance), in addition to the antitumor and antimicrobial properties, has a fundamental action that is to enhance the secretions of the gastrointestinal tract to promote the absorption of other active ingredients .

2 - The single active principle is not important, but the synergy of the whole complex is important

Excerpt from the chapter: The complexity of the natural drug

It has been established that more than the active substance of a drug is effective the "pool" of pharmacologically active substances present in the drug because between it and the other components are established useful synergisms towards the medicinal effects and / or antagonisms to the side effects, both they are harmful (toxic) or simply unwanted.

Always reporting it to our case, more than the active ingredient taken individually is important to the alliance of pharmacologically active substances present in the Aloe , as they are able to interact with each other usefully.

In fact, some substances taken singly can be toxic, in association with others, they become useful and medicative.

Conclusion of the Treaty

The leaf of the Aloe, in its entirety, represents a synergistic complex of active principles to which particular actions and applications, difficult to replace and reproduce, compete.

It is obvious that any attempt to purify the raw extract will change the behavior of the finished product.

More clearly, Aloe has a set of active ingredients that interact with each other, which have specific actions and applications that are difficult to replace and reproduce.

It is obvious that any attempt to purify the raw extract, such as removing aloin, sterilize or pasteurize the Aloe, does nothing but de-stress the effects of the finished product .

You might be interested in:

Where to buy a fresh and natural product, like the one made at home

If you have the chance, time and desire, making fresh juice at home is always the best choice.

However there are cases where this is not possible, or is even contraindicated.

For example, for people who live in particularly busy and polluted cities .

It is in fact known that Aloe is a plant that tends to absorb smog, smoke, radiation and pollutants.

In these cases, using it to produce juice, it could even be counterproductive, because you would end up taking many toxic substances to your body, substances that the plant has absorbed directly from the environment in which you live.

In other cases there could be a climate problem .

Aloe Arborescens tolerates heat and drought very well, on the contrary it is badly predisposed to the harsh climates of winter. So if you live in the mountains, or in northern Italy, you may not be able to grow Aloe.

So how to do it?

For all these people who are unable to grow Aloe and self-produce the juice, the Erbedimauro farm cultivates and produces fresh Aloe juices to order .

We do not stock, the juice is made just before shipping, shipping that takes place in 24, maximum 48h.

erbedimauro In addition to a fresh product, we guarantee :

  • plants grown in Italy (San Girolamo di Fermo) in the ground, in the countryside, far from any form of pollution (read where we are );
  • cultivation and 100% organic products;
  • adult Aloe Arborescens plants, with more than 5 years;
  • leaves harvested by hand early in the morning, before sunrise;
  • leaves worked in the darkroom, in the absence of light;
  • natural products, without preservatives, excipients, thickeners, sugars or other substances added;

On this page you will find the entire catalog of juices produced by our company.

Below are some of the best-selling products:

aloe juice classic recipe aloe juice vegan recipe aloe arborescens juice filtered without peel

In which cases is aloin contraindicated?

There are cases in which it is better to avoid aloin and other anthraquinone compounds.

Since these are substances with a laxative action , they can cause irritation in those intestines already irritated due to an inflammatory disease.

So if you are suffering from diseases such as colitis, diverticulitis , or worse from ulcerative colitis , or Crohn's disease , it is better to avoid taking drinks or products containing aloin.

In this regard, our farm produces two varieties of products, one based on Aloe Arborescens and the other based on Aloe Vera, without peel and without aloin. Both are organic, natural and without preservatives.

aloe vera juice without aloin filtered aloe arborescens juice


[ 1 ] Inhibition of the angiogenesis and growth of Aloin in human colorectal cancer in vitro and in vivo;
[ 2 ] Cytotoxicity of a natural anthraquinone (Aloin) against human breast cancer cells with and without ErbB-2: topoisomerase IIalpha coamplification;
[ 3 ] Aloin promotes A549 cell apoptosis via the reactive oxygen species-mitogen activated protein kinase signaling pathway and p53 phosphorylation;
[ 4 ] From the Cover: Aloin, a Component of the Aloe Vera Leaf Leaf, Induces Pathological Changes and Modulates the Composition of Microbiota in the Large Intestines of F344 / N Male Rats.

NB : All information published on this site is informative and should not be considered as advice, or medical prescriptions, or other.
mauro erbedimauroMauro Vallesi, a farmer

Fascinated by the many beneficial and healing properties of these plants and after having used them for a long time, today, with the help of my family, I cultivate with passion Aloe Arborescens, Aloe Vera and many other aromatic and medicinal plants. My philosophy is simple, it is to offer the highest quality of raw materials and to use exclusively artisan processes to produce my products. Rules seemingly simple, which serve to get the most out of my plants and my products.